Tumors application note
Tumors are conditions characterized by the abnormal growth of cells, usually stemming from genetic mutations. This process can lead to severe complications in organs such as the liver, lungs, and heart. Therefore, it becomes paramount to understand and track tumor progression in disease modeling.
Measuring matrix stiffness
In response to this challenge, our nanoindentors offer a unique solution. They empower researchers to measure the mechanical properties of tissues, providing valuable data that can serve as mechanical biomarkers for the disease. This represents a significant advancement in the field, especially considering that traditional methods of assessing tumors often rely on invasive procedures or indirect measures.
We provide application notes that delve into practical cases where researchers have utilized our nanoindentors in tumor research. Importantly, these notes highlight how these tools can accurately measure the stiffness of tumorous tissues and cells. This information is crucial because an increase in tissue stiffness (matrix stiffness) is a hallmark of tumor progression. Furthermore, the applications of our nanoindentors extend beyond cancer research. They find use in a variety of other fields, including materials science and engineering, where understanding the mechanical properties of materials is essential.
Pavone: high-throughput mechanical characterization platform for tumors
Enter Pavone, our high-throughput mechanical characterization platform for tumors. The mechanical properties of tumorous tissues and tumor cells play a crucial role in understanding the mechanobiology of tumors. To address these challenges, Pavone offers automated indentation mapping for studying tissues and mechanobiology.
Pavone’s automation capabilities enable researchers to obtain data on the spatial distribution of mechanical properties across the entire sample surface. Additionally, its user-friendly interface makes it accessible to researchers with varying levels of expertise, reducing the need for highly skilled operators and ensuring consistent and reliable mechanical characterization results.
The application notes we provide delve into practical cases where our nanoindentors have been used in tumor research. They highlight how these tools can accurately measure the stiffness of tumor tissues and tumor cells. This information is crucial, as an increase in tissue stiffness is a hallmark of tumor progression. Moreover, our nanoindentors are not just limited to tumor research. They can be used in a variety of other fields, including materials science and engineering, where understanding the mechanical properties of materials is essential.
Our team is committed to providing you with comprehensive information about the practical applications of our nanoindentors. These tools prove particularly useful in cancer research and disease modeling. One of the key areas where our nanoindentors excel is in measuring the matrix stiffness as a biomarker. This is crucial in tracking the progression of various cancer types, diseases affecting millions worldwide.