Unlock the power of
mechanobiology

Discover game-changing insights into mechanical cues at the bio-interface by...

Unlock the power of

mechanobiology

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News & Events

2011

We apply our unique technology to help our customers develop breakthrough medical treatments, and to get these to patients faster.

2012

The first step is to build a first prototype of a product that would demonstrate the added value of our unique fiber-sensing technology, allowing potential users to start working with it. Having the technology in the hands of users at this early stage turns out to be very important and proves immensely valuable for the further development of our optical fiber-sensing systems.

2013

Working together with key collaborators and users, who ultimately turned into our customers, we develop multiple product lines in different application fields across life sciences and industrial branches. We quickly understand that our solutions can solve problems which other technologies are not able to resolve.

2016

Growing steadily with an expanding product portfolio and revenue, the Optics11 has grown to a team of 18 young and enthusiastic employees across many disciplines, led by CEO Niek Rijnveld and CTO Grzegorz Gruca. The founders remain involved on a strategic level.

APRIL 2016

Value Creation Capital invests in Optics11 through its TechNanoFund. The experienced entrepreneurs support the further growth and development of Optics11 by playing an active role in the Advisory Board, together with the founders.

2018

Optics11 is partnering with Red Box Direct to open our US office in Boston, to better serve our US customers.

2019

As our Life Science and Industrial Sensing product lines become more distinct for their respective industries, we launch Optics11 Life to further develop our support to our life science division. Our Pavone is launched. A result of close collaboration and market-need, the Pavone enables the non-destructive analysis of structural and functional properties of cells and other biomaterials in near-physiological conditions, over time. A unique product that serves to advance both the fundamental and applied research branches.

2022

Optics11 Life receives €5 million in new venture capital from FORWARD.one and returning investor Value Creation Capital. The funding will support the rollout of new products applying Optics11 Life’s novel technology for experiments at scale requiring high-throughput screening of in vitro models and biomaterials.

2023

The Cuore is launched. A scalable and efficient solution, this 3D contraction force platform provides an accurate functional readout for engineered muscle bundles. The Cuore has hit the ground running and revolutionizes 3D tissue culture for therapy development in heart failure & neuromuscular diseases.

Find anything you need

Clients' FAQ

Based on your application and needs, different options are possible. You can contact us, and we’ll figure out together the most suitable way to test our instruments with your application.

By filling in the form on the product pages or the form on the right side of this page you can request a quotation for an instrument. An application specialist will contact you to discuss your needs.

The innovative fiber-optical nanoindentation probes which are pre-calibrated, re-usable, and robust make the Optics11 Life instruments unique. Besides, the solutions bridge the gap from nano-mechanics to macr-mechanics and are easy to use.

We use optical glass fibers to guide infrared laser-light through a cavity onto a cantilever. One part of the incoming wave is directly reflecting back into the fiber, whereas a second wave reflects from the cantilever and then propagates back into the fiber. Those two waves, same in wavelength, are shifted in phase when being superimposed. As the cantilever bends due to external stress, the phase changes 1:1 in relation to the cantilever bending. You can also watch the first video on this page: Piuma & Chiaro Nanoindenter Instruments.

Optics11 Life supplies scientific instruments worldwide directly or via distributors. Optics11 Life is based in Amsterdam (headquarters), has a local sales branch in Boston, USA (see contact page), and for the regions China and Japan Optics11 Life (see contact page) collaborates with high-quality local distributors.

Get in touch either by email: info@optics11.com or phone:

+31 20 598 8326 (headquarters) 

+1 781 613 2030 (USA)

with one of our application specialists.

Trusted by
experts

Key features

The technology of Optics11 Life is based on two key elements: fiber optic sensing and state-of-the-art mechatronics. This combination allows the company to develop cutting-edge measurement systems that can measure where others can’t.

Combine cell-scale / localized mechanical testing, microscopy and environmental control in one device for synchronized operation and control.

  • Mechanics: apply from 0.2 nN – 1.5mN, to characterize from 10 Pa – 1 G Pa.
  • Optics: brightfield, phase contrast, widefield fluorescence (optional)
  • Environmental control (optional): temperature, CO2, humidity

Implemented feedback loop enables quasi-static, stress relaxation/creep and dynamic indentation measurements with high accuracy in sensing and control of force and indentation-depth which is needed for capturing complex mechanical properties such as nonlinearity, adhesion, viscoelasticity and poroelasticity.

Where you grow and prepare your samples, you can measure. In well plates, petri-dishes, on glass slides.

Where you grow and prepare your samples, you can measure. In well plates, petri-dishes, on glass slides.

Define a set of operations to be run – well plate to move to specific wells, find focus, poke, that can then be repeated fully automated from well to well. Remove user variability/error.

Every probe is pre-calibrated and the software guides you through its preparation to ensure reliable results for every experiment.

Scale-up your mechanobiology research

With the capacity to run 20.000+ measurements or approximately 400 experiments a day (depending on complexity of the protocol*), the Pavone is optimized to fit into your biological workflow.

* Contact us for more details on protocols and experiment designs

Versatile yet precise - adaptability within any experiment

The Pavone is versatile like a Swiss pocketknife with the precision of a surgical blade; it allows high-resolution mechanical mapping from sub-cellular scale to whole tissue samples spanning up to 100cm2.

This innovative approach provides researchers with a versatile and accurate tool for characterizing the mechanical properties of a wide range of biological samples. The Pavone allows for automated mechanical measurements across scales and up to 5 orders of magnitude with a single probe.

Biologically relevant results

Measure your soft (biological) materials in situ and under near physiological conditions, enabling repeated and non-destructive measurements on live samples over time. This allows the use of mechanics as a label-free biomarker in e.g., disease modeling, therapy development, regenerative medicine, and 3D in vitro modeling.

Ease of use

With a 2-day training, an operator can start running experiments and become an experienced user in approximately 3 weeks of regular use. Minimal operator involvement is required, providing you the freedom to program complex protocols, with automated execution. As indicated by our users, it is as easy as “I tap, I measure, I get.”

Modular design – future proof

Scale up your Pavone by adding the fluorescence – correlation of mechanical information with molecular and structural characteristics – and/or the environmental module – control over the physiological environment of your samples.

Key features

The technology of Optics11 Life is based on two key elements: fiber optic sensing and state-of-the-art mechatronics. This combination allows the company to develop cutting-edge measurement systems that can measure where others can’t.

Combine cell-scale / localized mechanical testing, microscopy and environmental control in one device for synchronized operation and control.

  • Mechanics: apply from 0.2 nN – 1.5mN, to characterize from 10 Pa – 1 G Pa.
  • Optics: brightfield, phase contrast, widefield fluorescence (optional)
  • Environmental control (optional): temperature, CO2, humidity

Implemented feedback loop enables quasi-static, stress relaxation/creep and dynamic indentation measurements with high accuracy in sensing and control of force and indentation-depth which is needed for capturing complex mechanical properties such as nonlinearity, adhesion, viscoelasticity and poroelasticity.

Where you grow and prepare your samples, you can measure. In well plates, petri-dishes, on glass slides.

Where you grow and prepare your samples, you can measure. In well plates, petri-dishes, on glass slides.

Define a set of operations to be run – well plate to move to specific wells, find focus, poke, that can then be repeated fully automated from well to well. Remove user variability/error.

Every probe is pre-calibrated and the software guides you through its preparation to ensure reliable results for every experiment.

PLATFORMS THAT ACCELERATE TRANSLATIONAL RESEARCH

Whether your focus lies on mechanical measurements and characterization at the cell scale, or you work with muscle tissues, our platforms offer you precise, fast, and accurate outcomes. Discover more about how our products can help you accelerate and achieve your research goals. 

WHO WE ARE

We are a growing team of 60+ passionate people, headquartered in Amsterdam, the Netherlands. Learn more about our journey so far, meet our team of professionals, and our career opportunities. 

SERVICE & SUPPORT

From initial interest to full-scale implementation, and throughout the entire lifecycle of our instruments, we offer our customers a dedicated and customized experience. We focus on optimizing the functionality and operation of our instruments, to ensure peak efficiency, enhancing their research productivity.

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