With a wide range of application areas, across an array of samples, for various disease areas and testing needs, our measurement platforms provide you with precise insights into mechanical cues to advance your translational research.
Mechanobiology can be described as the intricate movement of forces within cells and tissues. We believe that having a better understanding of these forces allows for significant advancements in healthcare and therapy development. We design and develop life science instrumentation that performs precise measurements in near-physiological conditions to provide functional, easy-to-use readouts. Our solutions provide critical insights to further the discovery, development, testing and manufacturing of medical therapies.
Pavone is automated and optimized for the biological workflow. It is a high-throughput, reliable, and easy-to-use solution that measures the local mechanical properties of cells, biomaterials, and 3D in vitro models.
Cuore is a 3D contraction force platform that revolutionizes 3D tissue culture for therapy development in heart failure and neuromuscular diseases. It provides precise functional readouts for engineered muscle bundles.
Piuma is a compact, standalone, and manual nanoindentor enabling the exploration of mechanical properties from micro- to macro scales in near physiological conditions.
Chiaro is a microscope-compatible, manual nanoindentation system that allows you to combine unique mechanical insights with the imaging equipment of your choice. A compact yet powerful instrument to expand your lab infrastructure.
With a wide range of application areas, across an array of samples, for various disease areas and testing needs, we can provide you with precise insights into mechanical cues to advance your translational research. Learn more about our applications here.
Spheroids & organoids
Hydrogels
Extracellular matrix
Single cell and 2D cultures
Ex vivo tissue
Engineered muscle tissue
Engineered heart tissue
Wound healing
In vitro culturing
Eye care and medical devices
Tissue regeneration
Cartilage regeneration
Skin regeneration
Cultured meat
Drug screening/toxicity testing
Functional assays
Degradability testing
Quality control
Mechanobiology research
“Through my work on cardiac disease modelling with pluripotent stem cells (hiPSC’s), I see an emergent need for massive parallel end-to-end force testing technology on engineered heart tissue. This will enable more accurate phenotyping and more effective drug targeting during early drug development. Optics11 Life’s fiber sensing technology is uniquely qualified to offer a powerful solution.”
“Pavone enables us to test different materials and get the data we wanted to get so far, with yields in the high-90% range. Calibration is very straightforward and much easier than traditional technologies [for mechanical characterization. We’re able to get consistent measurements from day-to-day using the same probe. Pavone allows us to utilize mechanics in addition to transcriptional profiling to determine how the cell biology of our models compares to the cell biology within a patient.”
Boston, MA, September 26th, 2023 Optics11 Life Inc., an innovator in the development of user-friendly, robust nanoindenters for…
September breezed past in a whirlwind of emotions, innovations, and memorable insights. Amidst all the excitement of conferences…
Wounds arise from various causes, including surgery, injury, extrinsic factors (e.g., pressure, burns, and cuts), or illnesses like…
Researchers at the University of Twente (Netherlands) have designed advanced growth factor-delivering systems to mimic angiogenesis. To provide…
Hydrogels, a versatile class of biomaterials, play a central role in bioengineering and regenerative medicine. They are a…
Cancer is among the leading causes of death worldwide, accounting for nearly 10 million deaths in 2020, or…
We are a team of 60+ passionate people, headquartered in Amsterdam, the Netherlands. Over the past 13 years, we have been collaborating with researchers and scientists to accelerate research through the generation of mechanical insights. In close collaboration with our customers and with their research goals in mind, we work together to spearhead transformative discoveries and pioneer novel applications, improving human health using cutting-edge advancements in life science technology.
Whether your focus lies on mechanical measurements and characterization at the cell scale, or you work with muscle tissues, our platforms offer you precise, fast, and accurate outcomes. Discover more about how our products can help you accelerate and achieve your research goals.
With a wide range of application areas, across an array of samples, for various disease areas and testing needs, we can provide you with precise insights into mechanical cues to advance your translational research. Learn more about our applications here.
We are a growing team of 60+ passionate people, headquartered in Amsterdam, the Netherlands. Learn more about our journey so far, meet our team of professionals, and our career opportunities.
Resources
Contact