Cardiac Fibrotic ECM

Cardiac fibrosis disrupts the heart’s structure and function, leading to heart failure. However, understanding the mechanical and compositional changes within fibrotic tissue has remained a challenge for researchers. In collaboration with leading scientists from the International Clinical Research Center (ICRC) and King’s College London, our latest application note delves into how mechanical properties can reveal new insights into the progression of cardiac fibrosis.

This comprehensive application note covers:

  • The importance of mechanical properties in fibrosis research
  • Advanced nanoindentation techniques for studying cardiac-specific decellularized matrices (dECMs)
  • How pro-fibrotic conditions impact the heart’s extracellular matrix composition and function
  • New opportunities for drug discovery and fibrosis treatment

Unlock the full application note to explore how mechanical measurements can become essential tools in advancing cardiac fibrosis research.

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PLATFORMS THAT ACCELERATE TRANSLATIONAL RESEARCH

Whether your focus lies on mechanical measurements and characterization at the cell scale, or you work with muscle tissues, our platforms offer you precise, fast, and accurate outcomes. Discover more about how our products can help you accelerate and achieve your research goals. 

High-throughput nanoindentation and imaging platform

High-throughput functional measurements of 3D engineered muscle

Versatile, microscope-compatible nanoindenter for mechanobiology

Tabletop, easy-to-use nanoindenter for soft-material testing

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We are a growing team of 60+ passionate people, headquartered in Amsterdam, the Netherlands. Learn more about our journey so far, meet our team of professionals, and our career opportunities. 

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From initial interest to full-scale implementation, and throughout the entire lifecycle of our instruments, we offer our customers a dedicated and customized experience. We focus on optimizing the functionality and operation of our instruments, to ensure peak efficiency, enhancing their research productivity.

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