Cardiac fibrosis disrupts the heart’s structure and function, leading to heart failure. However, understanding the mechanical and compositional changes within fibrotic tissue has remained a challenge for researchers. In collaboration with leading scientists from the International Clinical Research Center (ICRC) and King’s College London, our latest application note delves into how mechanical properties can reveal new insights into the progression of cardiac fibrosis.
This comprehensive document covers:
- The importance of mechanical properties in fibrosis research
- Advanced nanoindentation techniques for studying cardiac-specific decellularized matrices (dECMs)
- How pro-fibrotic conditions impact the heart’s extracellular matrix composition and function
- New opportunities for drug discovery and fibrosis treatment
Unlock the full application note to explore how mechanical measurements can become essential tools in advancing cardiac fibrosis research.