News

Cell mechanical properties as a new biomarker for cancer

Cancer is among the leading causes of death worldwide, accounting for nearly 10 million deaths in 2020, or almost one in six. The most common causes of cancer death in 2022 were lung (1.80 million deaths), colon and rectum (916.000 deaths), liver (830.000 deaths), stomach (769.000 deaths), and breast (685.000 deaths).  Cancer arises from the …

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Mechanobiology of fibrotic-related diseases

Fibrotic diseases and tumor-associated fibrosis constitute a worldwide health problem that, together, are responsible for enormous morbidity and mortality. Approximately 1 in 8 people worldwide suffer from fibrotic-related diseases. Fibrotic diseases encompass a broad spectrum of clinical disorders, including systemic sclerosis, idiopathic pulmonary fibrosis, macular degeneration, chronic kidney disease, liver cirrhosis, and cardiac fibrosis. Similar …

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Published articles (2022) endorse Optics11 Life’s unique technology.

https://www.optics11life.com/wp-content/uploads/2022/11/ENGINEERED-MARBLE-LIKE-BOVINE-FAT-TISSUE.mp4 Written by Fabiany Da Costa Gonçalves and illustrated by Yashjit Gangopadhyay Studies on the mechanobiology of cells, spheroids, organoids, tissues, and biomaterials are developing rapidly using our Chiaro, Piuma, and Pavone Nanoindenters. Most studies have investigated diseases and new therapies in regenerative medicine. More than 400 publications have cited Optics11 Life Nanoindenters in leading …

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EPIC CEO INTERVIEW: Niek Rijnveld reveals his journey as the CEO of Optics11 Life

EPIC’s Photonics Technologies Program Manager, Antonio Castelo, interviews Niek Rijnveld, CEO of Optics 11 Life Optics11 Life is a fast-growing high-tech company based in Amsterdam that manufactures instruments to measure the forces and mechanical properties of soft materials, including biological samples Summary AMSTERDAM, Q3, 2022 – Optics11 Life was established to commercialize a promising fibre-top sensing …

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Optics11 Life raises €5 million in funding for superior life science instruments 

Funding will support expanded offerings for drug development, and regenerative medicine as fibre-optic instrument-maker broadens their presence in the life science market  The new investment will also bolster the leadership team and support U.S. expansion  AMSTERDAM, September 29, 2022 – Optics11 Life, the fibre optics life science instrumentation company, announced today €5 million in new …

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PUBLICATIONS Q1-Q4 2021

Hydrogels, Biofilms, Spheroids and many more applications were measured with our Piuma and Chiaro nanoindenters. This year alone, we were featured in 86 new publications in various scientific journals. The number of papers are projected to grow significantly each year.   The Impact Factor (IF) are based on the 5 journals that have the highest ranking within this list.   Nature – Nature Journal IF (49.9); Nature Chemical Biology IF (15.04); Nature Communications (14.9)  Bioactive Materials (14.12)  Chemical Engineerning Journal (13.07)  Biomaterials  – IF (12.4)  Acta Biomaterialia – IF (8.9)  Find the list of 2021 publications (Q1 Q4) to see how Piuma and Chiaro Nanoindenters were used for the categorized applications.  Biofilms  Films  Pereira, D. de M., Schumacher, M., & Habibović, P. (2021). Cobalt-containing Calcium Phosphate Induces Resorption of Biomineralized …

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Optics11 and Optics11 Life secure funding to accelerate growth

Niek Rijnveld, Optics11 & Optics11 Life CEO AMSTERDAM Optics11 and Optics11 Life have secured funding fromRabobank. The funding will be used to strongly accelerate growth acrossglobal markets, to further build the team for the future and tostrategically expand the high-tech product portfolios of both businessunits. “This is the right moment to pick up the pace. …

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Publications with Piuma and Chiaro Nanoindenters

Mechanical properties of spheroids and other biomaterials were measured with Piuma and Chiaro Nanoindenters, and featured in 39 new publications in various scientific journals:  Biofabrication (IF 8.2), Biomaterials (IF 10.3), Mechanics of Materials (IF 1.1), Materials Science and Engineering: C (IF 5.9), Nature Communications (IF 12.1), Experimental Mechanics (IF 2.5), Regenerative Biomaterials, Biomacromolecules (5.7), Acta Biomaterialia …

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Nanoindentation on Gummy Bears

When science and humor find each other, the results are truly amazing. Watch our Piuma Nanoindenter dissect these sugary little fellows. Let us know if you can guess a gummy bear’s stiffness? https://youtu.be/GohEHWyxkFE Interested in learning more about our products? You will find all the information you need on our Product page. Visit Product Page

Nanoindentation Publications Q1

Nanoindentation Publications Q1 We designed the Chiaro & Piuma Nanoindenters to enable researchers to measure a broad range of different samples! And they did! Already 24 scientific journal articles are published this year!    Here is the list of mechanically characterized samples included in these nanoindentation publications:   Cells and Tissues: Alteration in stiffness of corneal epithelium, basement membrane and stroma with age and obesity Cell nucleus – the mechanical role of lamins and chromatin CyPhyGels and  …

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