Hydrogel mechanics are a key driver in bioengineering
Mechanical properties of hydrogels can be adjusted across a wide range, allowing them to guide cell function and tissue development by mimicking the native ECM, regulating the delivery of biochemical compounds, and providing mechanical stimuli to the 3D cell constructs.
Cell mechanical properties as a new biomarker for cancer
Advanced mechanical characterization tools may deepen comprehension of cancer cell morphology and mechanics and their role in development, physiology, and disease. In this sense, Optics11 Life nanoindenters emerge as a powerful method for new therapeutic approaches for cancer.
Fibrotic diseases and tumor-associated fibrosis constitute a worldwide health problem that, together, are responsible for enormous morbidity and mortality. Approximately 1 in 8 people worldwide suffer from fibrotic-related diseases.Optics11 Life Nanoindenters emerge as a powerful method of mechanical characterization of fibrotic tissues.
Published articles (2022) endorse Optics11 Life’s unique technology
Studies on the mechanobiology of cells, spheroids, organoids, tissues, and biomaterials are developing rapidly using our Chiaro, Piuma, and Pavone Nanoindenters. More than 400 publications have cited Optics11 Life Nanoindenters in leading scientific journals.
Hydrogels, Biofilms, Spheroids and many more applications were measured with our Piuma and Chiaro nanoindenters. This year alone, we were featured in 86 new publications in various scientific journals. The number of papers are projected to grow significantly each year.
NEW PUBLICATIONS USING PIUMA AND CHIARO NANOINDENTERS
THE LIST OF NANOINDENTER APPLICATIONS KEEPS GROWING! At the end of 2019, seven new scientific papers featuring the measurements with the Piuma and the Chiaro nanoindenter were published in various well known scientific journals: Stem Cell Reports, Biomate…
We are very excited to share the news about the last three Chiaro indenter shipments that reached London, Marseille, and Barcelona!The group of Dr. Thomas Iskratsch at Queen Mary University has acquired the Chiaro indenter combined with fluorescence microscope to…
Introducing the next generation of Piuma & Chiaro Nanoindenters! Real-Time, Robust and improved Range What to expect of this next generation Piuma and Chiaro Nanoindenters? Hardware update Closed-loop XYZ stages with real-time sensing of tip position and much more….