Pavone: high-throughput mechanical characterization platform for hydrogels in various well-plates.
One of the characteristics of hydrogels is its mechanical properties that influence the morphology, biochemical signaling, and functioning of cells, and, therefore, should be similar to biological tissue. Typically, the mechanical characterization of hydrogel is time-consuming, and requires extensive sample preparation and expert skills. Furthermore, as many various sample configurations and conditions need to be tested, a high-speed indenter is necessary to perform hundreds of indentation measurements in a reliable and user-friendly manner. Therefore, we here present the high-throughput mechanical characterization platform PAVONE for automated indentation mapping of hydrogels.