Mechanobiology of organoids

Organoids are a significant tool for studying tumor progression and disease modeling due to their ability to emulate the architecture and functionality of real organs at a miniature scale. These lab-grown cellular structures offer a realistic platform to model tumor behavior in specific organs like the liver, lungs, or heart.

Measuring organoid stiffness

In response to the demand for accurate organoid modeling, our nanoindenters present an innovative solution. They equip researchers with the capability to quantify the mechanical properties of organoids, yielding crucial data that may act as mechanical biomarkers for disease states. This marks a significant leap forward, given that conventional approaches for organoid assessment often depend on invasive techniques or indirect estimations.

We offer application notes detailing real-world instances where our nanoindenters have been employed in organoid-based tumor research. Importantly, these notes underline how our tools can precisely measure the rigidity of organoid structures and cells. This data is vital because heightened organoid stiffness often signifies advanced disease progression, akin to increased matrix stiffness in actual tumors. Moreover, the applications of our nanoindenters are not restricted to cancer research. They are also applicable in diverse sectors like materials science and engineering, where the knowledge of material mechanical properties is critical.

Submit the form to download to the file

Interested in mechanobiology?

Discover latest

PLATFORMS THAT ACCELERATE TRANSLATIONAL RESEARCH

Whether your focus lies on mechanical measurements and characterization at the cell scale, or you work with muscle tissues, our platforms offer you precise, fast, and accurate outcomes. Discover more about how our products can help you accelerate and achieve your research goals. 

WHO WE ARE

We are a growing team of 60+ passionate people, headquartered in Amsterdam, the Netherlands. Learn more about our journey so far, meet our team of professionals, and our career opportunities. 

SERVICE & SUPPORT

From initial interest to full-scale implementation, and throughout the entire lifecycle of our instruments, we offer our customers a dedicated and customized experience. We focus on optimizing the functionality and operation of our instruments, to ensure peak efficiency, enhancing their research productivity.

Resources

Contact

Quote Form

Get latest insights

Product Inquiry