Mechanobiology of Tumors

Tumors are conditions characterized by the abnormal growth of cells, usually stemming from genetic mutations. This process can lead to severe complications in organs such as the liver, lungs, and heart. Therefore, it becomes paramount to understand and track tumor progression in disease modeling.

Measuring matrix stiffness

In response to this challenge, our nanoindenters offer a unique solution. They empower researchers to measure the mechanical properties of tissues, providing valuable data that can serve as mechanical biomarkers for the disease. This represents a significant advancement in the field, especially considering that traditional methods of assessing tumors often rely on invasive procedures or indirect measures.

We provide application notes that delve into practical cases where researchers have utilized our nanoindentors in tumor research. Importantly, these notes highlight how these tools can accurately measure the stiffness of tumorous tissues and cells. This information is crucial because an increase in tissue stiffness (matrix stiffness) is a hallmark of tumor progression. Furthermore, the applications of our nanoindenters extend beyond cancer research. They find use in a variety of other fields, including materials science and engineering, where understanding the mechanical properties of materials is essential.

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