mechanical

Exploring the Role of Mechanical Forces and the Potential of Nanoindentation for Monitoring and Accelerating the Healing Process

Wounds arise from various causes, including surgery, injury, extrinsic factors (e.g., pressure, burns, and cuts), or illnesses like diabetes and vascular diseases 1. Mechanical forces play an essential role in wound healing. The wound site’s mechanical environment affects cell activity and the quality of wound healing 2. Defects involving healing tissue result in fibrotic scars …

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Controlling vascular remodeling with Pavone Nanoindenter

Researchers at the University of Twente (Netherlands) have designed advanced growth factor-delivering systems to mimic angiogenesis. To provide long-term functionality to the designed vasculature, they enhanced the spatial and temporal control over the vascular endothelial growth factor (VEGF) within the 3D microenvironment to guide the vascular remodeling processes. Controlling cellular fate and functionality by modulating …

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